{"id":13753,"date":"2025-03-05T12:16:24","date_gmt":"2025-03-05T12:16:24","guid":{"rendered":"https:\/\/af-net.eu\/?page_id=13753"},"modified":"2025-03-26T13:46:59","modified_gmt":"2025-03-26T13:46:59","slug":"partnerstudie-caba-hfpef","status":"publish","type":"page","link":"https:\/\/www.af-net.eu\/en\/partnerstudie-caba-hfpef\/","title":{"rendered":"Partnerstudie – CABA-HFPEF"},"content":{"rendered":"\n
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CABA-HFPEF-DZHK27<\/strong><\/h2>\n\n\n\n
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CAtheter-Based ablation of Atrial fibrillation vs. conventional treatment in patients with Heart Failure with Preserved Ejection Fraction (CABA-HFPEF)<\/p>\n\n\n\n

Sponsor\u00b4s Protocol Code: CABA-HFPEF-DZHK27<\/p>\n\n\n\n

ClinicalTrials.gov Identifier: NCT05508256<\/p>\n<\/div>\n<\/div>\n<\/div><\/div>\n\n\n\n

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STUDY DESIGN<\/strong><\/h2>\n\n\n\n
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Investigator-initiated multicentre study with prospective parallel group comparison with randomised, open group allocation and blinded endpoint analysis (so-called PROBE design)<\/p>\n<\/div>\n\n\n\n

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Study objective<\/strong><\/h5>\n\n\n\n

The aim of the study is to investigate whether catheter ablation of atrial fibrillation (AF) can prevent serious cardiovascular events in patients with heart failure with preserved or mildly reduced ejection fraction (HFpEF or HFmrEF).<\/p>\n<\/div>\n\n\n\n

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Description<\/strong><\/h5>\n\n\n\n

Atrial fibrillation is an irregular heart rhythm in which the upper chambers of the heart (atria) beat very quickly. Atrial fibrillation can increase the risk of blood clots forming in the heart. These can break loose and travel to the brain, where they can trigger a stroke. Catheter ablation is a procedure that restores the normal heart rhythm. However, even patients who successfully undergo this treatment may have an increased risk of stroke compared to people who have never had atrial fibrillation.<\/p>\n<\/div>\n\n\n\n

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To reduce the risk of stroke, patients are prescribed one of two drugs after catheter ablation: a drug that inhibits the function of blood platelets (acetylsalicylic acid (ASA), e.g. Aspirin\u00ae) or a blood thinner (also known as an anticoagulant, e.g. rivaroxaban).The aim of this study is to find out which of these two types of treatment is best at preventing strokes.<\/p>\n<\/div>\n<\/div>\n<\/div><\/div>\n\n\n\n

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CONTACT INFORMATION<\/strong><\/h2>\n\n\n\n
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PD Dr. med. Abdul Parwani<\/strong><\/h5>\n\n\n\n

Principal Investigator<\/p>\n\n\n\n

Klinik f\u00fcr Kardiologie, Angiologie und Intensivmedizin
Deutsches Herzzentrum der Charit\u00e9 Berlin<\/p>\n\n\n\n

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FURTHER INFORMATION<\/strong><\/h2>\n\n\n\n
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Homepage<\/h4>\n\n\n\n

Charit\u00e9<\/a>
DZHK<\/a><\/p>\n\n\n\n

SPONSOR<\/h4>\n\n\n\n

Charit\u00e9 – Universit\u00e4tsmedizin Berlin<\/p>\n<\/div>\n\n\n\n

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AFNET ROLE<\/h4>\n\n\n\n

Regulatory EC submissions in Germany and Austria, committee support, ISF preparation, review of study documents, organisation of investigator meetings, social media<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div><\/div>\n","protected":false},"excerpt":{"rendered":"

CABA-HFPEF-DZHK27 CAtheter-Based ablation of Atrial fibrillation vs. conventional treatment in patients with Heart Failure with Preserved Ejection Fraction (CABA-HFPEF) Sponsor\u00b4s Protocol Code: CABA-HFPEF-DZHK27 ClinicalTrials.gov Identifier: NCT05508256 STUDY DESIGN Investigator-initiated multicentre study with prospective parallel group comparison with randomised, open group allocation and blinded endpoint analysis (so-called PROBE design) Study objective The aim of the study … Read more<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","iawp_total_views":9,"_vp_format_video_url":"","_vp_image_focal_point":[],"footnotes":""},"class_list":["post-13753","page","type-page","status-publish"],"acf":[],"uagb_featured_image_src":{"full":false,"thumbnail":false,"medium":false,"medium_large":false,"large":false,"timeline-express":false,"timeline-express-thumbnail":false,"1536x1536":false,"2048x2048":false,"vp_sm":false,"vp_md":false,"vp_lg":false,"vp_xl":false,"vp_sm_popup":false,"vp_md_popup":false,"vp_xl_popup":false},"uagb_author_info":{"display_name":"admin","author_link":"https:\/\/www.af-net.eu\/en\/author\/cre8ors\/"},"uagb_comment_info":0,"uagb_excerpt":"CABA-HFPEF-DZHK27 CAtheter-Based ablation of Atrial fibrillation vs. conventional treatment in patients with Heart Failure with Preserved Ejection Fraction (CABA-HFPEF) Sponsor\u00b4s Protocol Code: CABA-HFPEF-DZHK27 ClinicalTrials.gov Identifier: NCT05508256 STUDY DESIGN Investigator-initiated multicentre study with prospective parallel group comparison with randomised, open group allocation and blinded endpoint analysis (so-called PROBE design) Study objective The aim of the study…","_links":{"self":[{"href":"https:\/\/www.af-net.eu\/en\/wp-json\/wp\/v2\/pages\/13753","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.af-net.eu\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.af-net.eu\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.af-net.eu\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.af-net.eu\/en\/wp-json\/wp\/v2\/comments?post=13753"}],"version-history":[{"count":17,"href":"https:\/\/www.af-net.eu\/en\/wp-json\/wp\/v2\/pages\/13753\/revisions"}],"predecessor-version":[{"id":14225,"href":"https:\/\/www.af-net.eu\/en\/wp-json\/wp\/v2\/pages\/13753\/revisions\/14225"}],"wp:attachment":[{"href":"https:\/\/www.af-net.eu\/en\/wp-json\/wp\/v2\/media?parent=13753"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}