{"id":11393,"date":"2024-08-14T12:57:36","date_gmt":"2024-08-14T12:57:36","guid":{"rendered":"https:\/\/www.friendly-bartik.94-130-216-58.plesk.page\/gap-af\/"},"modified":"2024-12-16T13:07:53","modified_gmt":"2024-12-16T13:07:53","slug":"gap-af","status":"publish","type":"page","link":"https:\/\/www.af-net.eu\/en\/gap-af\/","title":{"rendered":"Gap-AF"},"content":{"rendered":"\n
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\"\"<\/figure>\n<\/div><\/div>\n\n\n\n
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Gap-AF<\/strong>-AFNET 1<\/h2>\n\n\n\n
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Catheter ablation of arial fibrillation by linear pulmonary vein isolation<\/p>\n<\/div>\n<\/div>\n<\/div><\/div>\n\n\n\n

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Study design<\/strong><\/h2>\n\n\n\n
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Randomized trial to investigate the significance of complete versus incomplete electrical isolation of pulmonary veins by radiofrequency-induced linear lesions in patients with paroxysmal atrial fibrillation<\/p>\n<\/div>\n\n\n\n

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\"\"<\/figure>\n<\/div>\n<\/div>\n\n\n\n
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Inclusion Criteria<\/strong><\/h5>\n\n\n\n

\"\" Idiopathic paroxysmal symptomatic atrial fibrillation refractory to antiarrhythmic therapy<\/p>\n\n\n\n

\"\" Age 50 – 85 years<\/p>\n\n\n\n

\"\" Patient willing to participate in randomized trial and an invasive follow-up at month 3 (-6)<\/p>\n\n\n\n

\"\" Structural normal heart<\/p>\n\n\n\n

\"\" Patient willing and able to participate in 12 months follow-up period<\/p>\n\n\n\n

\"\" ECG documentation of atrial fibrillation (ECG, Holter, event recorders, etc) for at least one AF event in the prior year (related to symptomatic or asymptomatic episodes) with an average number of one episode per month<\/p>\n\n\n\n

\"\" Written informed consent of the patient<\/p>\n<\/div>\n\n\n\n

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Exclusion Criteria<\/strong><\/h5>\n\n\n\n

\"\" Patients who have had previous pulmonary vein ablation procedures Patients with atrial fibrillation secondary to a reversible cause<\/p>\n\n\n\n

\"\" Known presence of intracardiac or other thrombi<\/p>\n\n\n\n

\"\" Evidence of obstructive lung disease requiring bronchodilator therapy<\/p>\n\n\n\n

\"\" Pregnant females or those of childbearing potential who have not had a negative pregnancy test within 48 hours before treatment.<\/p>\n\n\n\n

\"\" Other medical illness (i.e. cancer, congestive heart failure) that may cause the patient to be non-compliant with the protocol, confound the data interpretation or is associated with limited life-expectancy (i.e., less than one year)<\/p>\n\n\n\n

\"\" History of bleeding diathesis or suspected pro-coagulant state contraindication to anticoagulation therapy<\/p>\n\n\n\n